ea0063p1015 | Interdisciplinary Endocrinology 2 | ECE2019
Felicetti Francesco
, Cento Alessia Sofia
, Fornengo Paolo
, Cassader Maurizio
, Mastrocola Raffaella
, D'Ascenzo Fabrizio
, Settanni Fabio
, Benso Andrea
, Arvat Emanuela
, Collino Massimo
, Fagioli Franca
, Aragno Manuela
, Brignardello Enrico
Cardiovascular (CV) diseases significantly contribute to the mortality excess observed in survivors of pediatric acute lymphoblastic leukemia (ALL) who received hematopoietic stem cell transplantation (HSCT). The study explores advanced glycation end-products (AGEs) levels, inflammatory status and lipid profile in a cohort of ALL survivors, in order to investigate their potential role in the pathogenesis of CV late effects. Inclusion criteria were: a) previous diagnosis of ALL...